I’m a British neuroscientist and writer who’s been using computers to study the brain since 1998, and writing about it since 2016. How I ended up a neuroscientist is hard to explain, for my formative years were spent devouring science books that were not about the brain. That’s partly because finding worthwhile books about the brain is so hard – few delve into how the brain actually works, into the kinds of meaty details that, for example, Hawking offered us on physics and Dawkins on evolution. So I wrote one to solve that problem; and the books on my list are just that too: deep, insightful works on how the brain does what it does.
I wrote
The Spike: An Epic Journey Through the Brain in 2.1 Seconds
A fast-moving, endlessly fascinating, yet deeply scholarly history of how we know what we know about the brain. Cobb’s magnum opus traces how our definition of the brain has evolved over the centuries, and is still evolving now. I’ve called it a history, and it says as much on the cover of the UK version, but a good third of the book is actually about the cutting edge of neuroscience, of the marvellous ways we now have of interrogating the brain, and where they may take us in the future.
This is the story of our quest to understand the most mysterious object in the universe: the human brain.
Today we tend to picture it as a computer. Earlier scientists thought about it in their own technological terms: as a telephone switchboard, or a clock, or all manner of fantastic mechanical or hydraulic devices. Could the right metaphor unlock the its deepest secrets once and for all?
Galloping through centuries of wild speculation and ingenious, sometimes macabre anatomical investigations, scientist and historian Matthew Cobb reveals how…
The author’s opening line calls this slim volume “fictional science”, a genre all of its own. It remains a unique and compelling book, a set of simply stated ideas that show how apparently complex behaviour can emerge from the simplest of brains. On another reading, it is a parts list for what functions brains must have evolved. However I read it, it’s been instrumental in shaping how I think about the brain.
These imaginative thought experiments are the inventions of one of the world's eminent brain researchers.
These imaginative thought experiments are the inventions of one of the world's eminent brain researchers. They are "vehicles," a series of hypothetical, self-operating machines that exhibit increasingly intricate if not always successful or civilized "behavior." Each of the vehicles in the series incorporates the essential features of all the earlier models and along the way they come to embody aggression, love, logic, manifestations of foresight, concept formation, creative thinking, personality, and free will. In a section of extensive biological notes, Braitenberg locates many elements of…
A magnificent synthesis of Bialek and colleagues’ research into how spikes from neurons send information. A strong contender for the most readable serious science book ever published. Even if you only understand a quarter of it (as I did on first reading as a math-shy grad student), the sheer quantity of ideas and the flow of the prose is mind-blowing. As essential a read now as it was in 1997, these ideas have not dated one bit.
What does it mean to say that a certain set of spikes is the right answer to a computational problem? In what sense does a spike train convey information about the sensory world? Spikes begins by providing precise formulations of these and related questions about the representation of sensory signals in neural spike trains. The answers to these questions are then pursued in experiments on sensory neurons. Intended for neurobiologists with an interest in mathematical analysis of neural data as well as the growing number of physicists and mathematicians interested in information processing by "real" nervous systems, Spikes provides a…
The authors hilariously claim in their acknowledgements that this is a short book. It is not. Instead, it is a volume that explains ten key principles of why brains work the way they do, from why they do so much computation with chemistry to the irreducible smallness of a brain’s components. A densely argued, fiercely detailed book, not one for the faint of heart – but one that has pride of place on the shelves of many neuroscientists, mine included.
Two distinguished neuroscientists distil general principles from more than a century of scientific study, “reverse engineering” the brain to understand its design.
Neuroscience research has exploded, with more than fifty thousand neuroscientists applying increasingly advanced methods. A mountain of new facts and mechanisms has emerged. And yet a principled framework to organize this knowledge has been missing. In this book, Peter Sterling and Simon Laughlin, two leading neuroscientists, strive to fill this gap, outlining a set of organizing principles to explain the whys of neural design that allow the brain to compute so efficiently.
We neuroscientists know a lot about how brains are, but not how they come to be. This book fills that huge hole: it explains how genetics and development shape the growing brain, and the consequences this has for our personalities and our mental disorders. Mitchell’s thesis is that the stochastic nature of development is key to understanding much of the variation between brains, and it has changed the way I think about the wiring of brains.
A leading neuroscientist explains why your personal traits are more innate than you think
What makes you the way you are-and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive…
We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them.
Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action.
After Dr. Shawn Jennings, a busy family physician, suffered a brainstem stroke on May 13, 1999, he woke from a coma locked inside his body, aware and alert but unable to communicate or move. Once he regained limited movement in his left arm, he began typing his story, using one hand and a lot of patience.
With unexpected humour and tender honesty, Shawn shares his experiences in his struggle for recovery and acceptance of his life after the stroke. He affirms that even without achieving a full recovery life is still worth…
Locked In Locked Out: Surviving a Brainstem Stroke
After Dr. Shawn Jennings, a busy family physician, suffered a brainstem stroke on May 13, 1999, he woke from a coma locked inside his body, aware and alert but unable to communicate or move. Once he regained limited movement in his left arm, he began typing his story, using one hand and a lot of patience.
With unexpected humour and tender honesty, Shawn shares his experiences in his struggle for recovery and acceptance of his life after the stroke. He affirms that even without achieving a full recovery life is still worth…
